Nature’s Most Powerful, Safe & Effective Pain Reliever

Inflammation is the body’s reaction following an injury, like when you develop back pain. It helps speed up recovery from sprains, strains, fractures, bruises, contusions, surgery and arthritis.

Doctors prescribe NSAIDs to reduce inflammation and even painkillers to block the pain signals. The problem with these medications are that they only provide temporarily relief and do not deal with the underlying cause.

But that’s not the worst of it all, most pain sufferers worldwide are still willing to ACCEPT these dreadful, mind-fogging, life-shortening side effects when they start new pain medication… they're literally INCREASING the amount of pain your body is in.

Even though there are safe alternatives available…

Mother Nature’s Most Powerful, Safe & Effective
Pain Reliever

It's called Proteolytic Enzymes, a systemic enzyme, which work to reduce the inflammation and promote healing without any side effects.

The word systemic means whole body and systemic enzymes operate throughout your body in every system and organ. Enzymes are more important than vitamins and minerals for general health. Without enzymes, vitamins and minerals are useless. Enzymes are catalysts for metabolic processes and digestion.

Enzymes are the main line of defense against inflammation.

Enzymes are not anti-inflammatory drugs but rather reduce inflammation by neutralizing the bio-chemicals of inflammation to levels where the creation, repair and regeneration of injured tissues can take place.

To understand how this inflammation process works we need to take a closer look what happens first in the body…

When you injure yourself, fibrin is released. Fibrin is a natural substance in your body which helps in wound healing. It's also what scar tissue and scabs are made of.

So in other words when your body senses an injury, which can be as minor as a small bump, scratch or even just sudden heat or cold it will react as follows:

Phase 1 – White blood cells are send to the injured or irritated area to fight infection, causing inflammation and swelling.
Phase 2 – Fibrins are being released to essentially "seal off the site" with a strong protective mesh.

In NORMAL circumstances the site is healed, the fibrin breaks down, the inflammation subsides, and everything goes back to normal.

fibrin spiderwebs enzymes

Red blood cells get stuck in fibrin, due to lack proteolytic enzymes in blood stream

But unfortunately a lot of the time this process goes wrong... causing the development of spiderwebs of scar tissue and will be pumped through your body!

Sometimes, our bodies fail to "call off" the fibrin. Imagine an on & off switch, in this case the switch is stuck in the ‘ON’ position. This means fibrin continues to build up around the site, then harden, causing further inflammation, and often…

...excruciating pain that just won't go away.

Research studies show that if you're over 50, once inflammation is triggered, it's much less likely to go back down, thus a struggle with chronic pain starts.medicine science sports journal

A study published in the Journal of Medicine, Science, Sports and Exercise found that "proteolytic enzymes have therapeutic effects in the treatment of inflammation and soft tissue injuries."

Unfortunately, this function of this enzyme is mostly unknown in America, Australia, and the UK.

It was Dr. Max Wolf whom discovered first after doing extensive research, that when the body was reacting to pain, the bodies of young people responded by flooding the painful area with something called "proteolytic enzymes".

But to his amazement, the older the people in his research studies the more drastic reduced levels of proteolytic enzymes were found. At the same time, they felt a lot more pain too.

Excited by his amazing discovery, he decided to narrow it down even further. Later on he discovered that people in their late twenties, early thirties starting to show diminishing proteolytic enzymes levels in their body.

Proteolytic Enzymes are the ‘Shut Off’ Switch for Pain

You can imagine that when Dr Wolf released his research info about how proteolytic enzymes are the ‘shut off’ switch for pain to the scientific community, he was frownedr max wolf discovered proteolytic enzymes inflammationd upon by many colleagues …

But when they did their own research into this they discovered to their own amazement that proteolytic enzymes were indeed the body’s own way in fighting inflammation and pain.

But these enzymes are also important in other areas of our health…

In Addition To Reducing Inflammation and Eliminating Pain, These Enzymes Also...

I already touched upon the importance of proteolytic enzymes versus fibrin development and how this fibrin can continue to develop (switch stuck in ‘on’ position scenario), but I will include this again here with some other important functions this enzyme has…

1) Break down scar tissue and fibrosis – Fibrosis is scar tissue that builds up in our bodies and over time creates some much restriction and strain on our organs that they can no longer function.

That is where the systemic enzymes come in to play, they eat away that excess build up of fibrin and scar tissue.

And believe it or not, doctors throughout Europe and Asia have been using them for over 50 years to remove scar tissue from surgical wounds, kidney fibrosis, pulmonary fibrosis and in numerous other scenarios.

So why not in the UK or US? No idea…

2) Cleanse toxins from the blood stream – Maybe you already know that our body gets rid of toxins via our blood. And it is the proteolytic enzymes that soak up these toxins.

But at the same time these systemic enzymes also help the blood to be cleansed of access fibrin build up. The fibrin causes the blood to thicken and chances of cloths increase and with it heart attacks or strokes.

Important Notice! For those whom are a haemophiliac or have been prescribed blood thinners, it is of upmost importance to first consult with your doctor before contemplating using systemic enzyme therapy.

3) Healthy Immune System – Proteolytic enzymes recognise viruses, so when the immune system is low and we become more susceptible to infections, the enzymes clean the blood to help fight off infection.

On the other hand when the immune system is in too high gear (working too hard), as with auto-immune diseases, these enzymes work to tone down the immune system and eat the antibodies that are attacking the healthy tissue.

Pretty amazing right…?!

Other important functions of these enzymes…

Proteolytic enzymes or protease can be used, in part, to digest complete proteins that are in meat. But they have also been harnessed for a multitude of healing processes, sometimes exclusively and sometimes in conjunction with other therapies.

Some of these areas they can have immediate impact on are, improved heart health, cancer prevention and recovery, and even Alzheimer's prevention.

For over 50 years now, in Europe and Japan, proteolytic enzymes or protease are used to speed up healing from bodily injury or surgery. They are incorporating enzyme therapies with mainstream medicine.systemic enzymes cancer

An example of a study in the use of systemic enzyme therapy with cancer was done by Dr. Nicholas Gonzalez and Dr. Linda Isaacs.

[1] Although it was the once defamed and now deceased William Donald Kelley, DDS, who started the research initially. He created a metabolic enzymatic cancer therapy to cure his pancreatic cancer, which led to the cure of thousands of various cancers over a period of two decades.

Now Dr. Gonzales and Isaacs are working wonders on cancer patients in NYC.

You can safely say that systemic enzymes truly are one of nature's most powerful natural remedies?

For those of you suffering from any sort of ache or pain, I urge you to consider systemic enzymes. They have been used to safely and effectively eliminate pain and inflammation from all sorts of conditions like...

- Arthritis,
- back pain,
- sciatica,
- or any type of joint pain…

But on the other hand if your health is important to you it is also very beneficial as it well known to help with conditions like…

…heart disease, cancer, chronic fatigue, fibromyalgia and more.

So the remaining question is, ‘how do we get enough of these enzymes in our body’?

Our Diet Does NOT Provide High Enough Levels for
Effective Pain Relief

So the simple answer is…SUPPLEMENTATION!

Unfortunately, it is the only way to raise the levels high enough.

Why You Need to Supplement?

In a perfect world, we would all eat raw (organic) unprocessed foods that are naturally high in active enzymes.

But this isn't a perfect world.

Most people eat food that is enzyme deficient (cooking and processing destroy enzymes) and fail to chew food adequately (saliva contains amylase) so their bodies must compensate. The body is forced to divert its production of metabolic proteolytic enzymes into the production of large amounts of pancreatic enzymes in order to break down all of the dead food in our diets.

Short term, this is not a problem. Your body can easily handle it. But the long-term consequences of this diversion are enormous. It can lead to everything from a weakened immune system to thickened blood, from pain and inflammation to cardiovascular disease, and from reduced athletic performance to difficulty breathing. Supplementing with proteolytic enzymes offsets this devastating diversion and restores balance.

If you decide to start taking Proteolytic Enzyme, than please make sure it is capsule based (or powder – I find capsules easier) so its easier for the body to absorb fully…

What Constitutes a Good Systemic Proteolytic Enzyme Formula?

So what should you look for in a properly designed supplemental proteolytic enzyme formula?

First, it needs a lot of protease. You want at least 200,000 HUT. This is far more than you will ever find in a digestive formula. 300,000 HUT is even better. And you will want to use vegetarian enzymes since they are much more tolerant of stomach acid and work in a much wider range of pH environments.

Second, you also want a good variety of enzymes which utilize different biological pathways and whose benefits complement, rather than duplicate, each other.

Third, there are some non-proteolytic enzyme ingredients that you will also want to include in the formula both because they increase the efficacy of the proteolytic enzymes in the formula and because they provide their own complementary benefits as well.

With that said, let's now take a look at the ingredients that should be included in what is considered the ideal systemic, proteolytic enzyme formula...

  • Fungal Protease and Fungal Pancreatin (particular strains of vegetarian protease enzymes)
  • Bromelain and Papain (The Plant Enzymes)
  • Nattokinase
  • Seaprose-S (instead of serrapeptase)
  • Rutin & Ginger (Non-enzymes naturally reduce inflammation)
  • CMIK-pH+™ Mineral Blend (pH balancing for maximising beneficial effects)

Some may also have some added pain relieving herbs thrown in.

Seaprose-S versus Serrapeptase

Serrapeptase is unfortunately used in many formulas instead of seaprose and sometimes along with it. Like seaprose, serrapeptase has remarkable anti-inflammatory and anti-edemic (counters swelling and fluid retention) activity in a number of tissues. And like seaprose, it can reduce pain and help clear mucous from the lungs by reducing neutrophil numbers, thus thinning the mucous in the lungs of patients with chronic airway diseases.

So why not use serrapeptase? Three reasons:

  1. Its quality tends to be inconsistent
  2. It can cause intestinal distress
  3. It is very sensitive to stomach acid, which means it has to be enteric coated. Unfortunately, the technology for enterically coated capsules is not reliable (which is why you normally find enteric coating used only on hard tablets or on hard beads inside capsules - as in cold capsules)

Seaprose-S, on the other hand is:

  • Manufactured in Japan and is of consistent high quality
  • Causes virtually no intestinal distress
  • Unaffected by stomach acid so it does not require enteric coating
  • And studies have shown that it is more effective than serrapeptase -- 85% vs 65%

The bottom line is that serrapeptase is harder to work with, produces side effects, can't handle stomach acid, and has to be used in an enterically coated capsule.

One of my personal favourites is pHi Zymes by Baseline Nutritionals Capsules, as they adhere to all of the standards mentioned above for making a quality systemic proteolytic enzyme…

systemic proteolytic enzymes inflammation

The following actions will improve the benefits you derive from supplementing with proteolytics:

  • Add more raw foods to your diet.
  • Cut out (or at least cut down) on processed foods.
  • Cut out (or at least cut down) on cooked foods.
  • Chew your food properly so they thoroughly mix with the enzymes in your saliva.
  • Drink alkalinized water--but not with your meals as it dilutes your digestive juices.

When to take it - dosing

For most people, proteolytic enzymes should be taken on a daily basis, at least 1 hour before eating (3 times per day generally). This is all that's needed to fight inflammation and pain and give you the best shot at maintaining a healthy inner environment.

You can try at your local health food shop, maybe pharmacy, but if they don’t know what systemic enzymes are, I wouldn’t go back there… in my eyes not knowledgeable on health issues and related supplements, but that is my take on it…

Effective Pain Relief WITHOUT Risking Your Health

Being able to get effective pain relief, without putting the health of your body's most important vital organs such as your liver and kidneys at risk...

... shouldn't that be a no-brainer for you?

I really hope you think so!

prescription medication roulette dangers naisdsIf you've been struggling with chronic back pain or joint pain and are desperate for it to simply GO AWAY without having to worry about the nasty side effects of NSAID's or other prescription pain medications, than I can personally highly recommend systemic enzymes.

So hopefully now I've opened up your eyes to a whole new world where science has finally broken through and given us what we consider to be the single most powerful 100% safe all-natural inflammation & pain relieving formula ever created.

With this in mind you now hopefully realise you are playing prescription roulette each time you take pain meds…

…What will you do about it?




[1] Gonzalez NJ and Isaacs LL: Evaluation of pancreatic proteolytic enzyme treatment of adenocarcinoma of the
pancreas, with nutrition and detoxification support. Nutr Cancer 1999;33:117-24.

[2] G. Klein and W. Kullich, "Reducing Pain by Oral Enzyme Therapy in Rheumatic Diseases," Wien Med Wochenschr 149 (1999): 577-80.

March 17, 2009

[4] Taussig S. Batkin S. Bromelain, the enzyme complex of pineapple (Ananas comosus) and its clinical application. An update. J Ethnopharmacol, 1988;22:191-203.

[5] Goldberg, D. M.: Enzymes as agents for the treatment of disease. Clin. Chim. Acta 206: 45 - 76 (1992)

[6] Teresita Guardia, Alejandra Ester Rotelli, et al. "Anti-inflammatory properties of plant flavonoids. Effects of rutin, quercetin and hesperidin on adjuvant arthritis in rat." Il Farmaco Volume 56, Issue 9, 1 August 2001, Pages 683--687.

[7] Fossati A. "Anti-inflammatory effects of seaprose-S on various inflammation models."  Drugs Exp Clin Res. 1999;25(6):263-70.

[8] Fujita M., Nomura K., Hong K., Ito Y., Asada A. and Nishimuro S.  "Purification and Characterization of a Strong Fibrinolytic Enzyme (Nattokinase) in the Vegetable Cheese Natto, a Popular Soybean Fermented Food in Japan." Biochemical and Biophysical Research Communications, Vol. 197, Issue 3, 30 December 1993, pp. 1340-1347.

[9] Rakhimov MR. "Anti-inflammatory activity of domestic papain]." Eksp Klin Farmakol. 2001 Jul-Aug;64(4):48-9.

[10] Fitzhugh DJ1, Shan S, Dewhirst MW, Hale LP. "Bromelain treatment decreases neutrophil migration to sites of inflammation." Clin Immunol. 2008 Jul;128(1):66-74.

[11] Stauder G. "Pharmacological effects of oral enzyme combinations." Cas Lek Cesk. 1995 Oct 4;134(19):620-4.

[12] Taraye JP. Lauressergues H. Advantages of a combination of proteolytic enzymes, flavonoids and ascorbic in comparison and non-steroidal inflammatory agents. Arzneim Forsch, 1977;27(1):1144-49.

[13] Mazurov VI, et al. Beneficial effects of concomitant oral enzymes in the treatment of rheumatoid arthritis. Int JTiss React 1997;19:91.
By | 2017-01-14T20:33:57+00:00 January 26th, 2016|

About the Author:

He is a Physiotherapist, specialising in back pain, author and known as a rebel in the back pain industry. He has 24 years clinical experience, having helped hundreds of patients in his clinic and thousands worldwide to overcome back pain. He is on a mission to change how spinal conditions are treated...